c-Jun(Thr91+Thr93) Antibody, Cy5 Conjugated

bs-4601R-Cy5

0.1ml

368 EUR

Cy5

3725

Cy5.5

IF(IHC-P)

anticorps

Polyclonal

1ug per 1ul

Thr91+Thr93

Phosphorylation

625,650nm/670nm

c-Jun Thr91+Thr93

Human, Mouse, Rat

IF(IHC-P)(1:50-200)

Polyclonal antibody

Conjugated Primary Antibodies

Rabbit (Oryctolagus cuniculus)

This antibody was purified via Protein A.

c-Jun(Thr91+Thr93) Polyclonal Antibody, Cy5 Conjugated

This is a highly specific antibody against c-Jun Thr91+Thr93.

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

KLH conjugated synthetic phosphopeptide derived from human c-Jun around the phosphorylation site of (Thr91+Thr93)

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.

p-c-JunThr91+Thr93; c-Jun phospho Thr91+Thr93; c-Jun phospho T91+T93; p-c-Jun Thr93; Jun oncogene; JUN; Activator Protein 1; AP 1; AP1; AP-1; Enhancer Binding Protein AP1; Jun Activation Domain Binding Protein; JUN protein; JUNC; p39; Proto oncogene cJun; Transcription Factor AP1; V jun avian sarcoma virus 17 oncogene homolog; vJun Avian Sarcoma Virus 17 Oncogene Homolog; JUN_HUMAN; Transcription factor AP-1; Activator 1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog.

C-jun (Oncoprotein C-jun) is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements and appears to be a major downstream target of the SAPK/JNK signaling pathway. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways. The MAP kinase homologue, SAPK/JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. In addition, the activity of SAPK/JNK is stimulated by the same signals that activate c-Jun.