c-Jun(Ser243) Antibody

bs-3173R

0.1ml

281 EUR

3725

Ser243

anticorps

1ug per 1ul

Unconjugated

c-Jun Ser243

Phosphorylation

Human, Mouse, Rat

c-Jun(Ser243) PAb

Primary Antibodies

Polyclonal antibody

Polyclonal antibody

WB, IHC-P, IF(IHC-P)

c-Jun(Ser243) Primary Polyclonal Antibody

This antibody was purified via Protein A.

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

This is a highly specific antibody against c-Jun Ser243.

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

KLH conjugated synthetic phosphopeptide derived from human c-Jun around the phosphorylation site of Ser73

Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.

If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

c-Jun phospho S243; c-JunSer243; Jun oncogene; JUN; Activator Protein 1; AP 1; AP1; AP-1; Enhancer Binding Protein AP1; Jun Activation Domain Binding Protein; JUN protein; JUNC; p39; Proto oncogene cJun; Transcription Factor AP1; V jun avian sarcoma virus 17 oncogene homolog; vJun Avian Sarcoma Virus 17 Oncogene Homolog; JUN_HUMAN; Transcription factor AP-1; Activator 1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog.

C-jun (Oncoprotein C-jun) is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements and appears to be a major downstream target of the SAPK/JNK signaling pathway. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways. The MAP kinase homologue, SAPK/JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. In addition, the activity of SAPK/JNK is stimulated by the same signals that activate c-Jun.