JNK1/2, c-Jun N-terminal Kinase

Catalog no.

AS16 4011

Size

100 µg

Price

675 EUR

Buy this product

Click here to buy JNK1/2, c-Jun N-terminal Kinase at gentaur.com

Raised in

Mouse

Available ordering format

Liquid

Clonality

Monoclonal

Clone

279Q38, IgG1

Molecular weight (expected | аpparent)

see datasheet

TAIR number

Refer to NCBI

Possible reactivity

to be determined

Storage condition

Store at -20°C.

Verified reactivity

Human, Mouse, Rat

Verified applications

Western blotting (WB)

Purification

Protein A/G purified.

Connected products

anti-mouse secondary antibodies

Protein number

Q9ESN9!!AIR8!!Q9UPT6!!AIR8!!B0VXR4

Supplementary information

Contact Gentaur support center at [email protected]

How to reconstitute

See included datasheet or contact our support service

References

To be added when available, antibody released in November 2016.

No reactivity

No confirmed exceptions from predicted reactivity known at the moment.

Recommended dilutions for use

0.5-1 µg/ml (WB), optimal concentrations should be determined by serial dilutions.

Immunogen

Recombinant human c-Src expressed in E. coli. UniProt: Mouse: Q9ESN9, Human: Q9UPT6, Rat: B0VXR4

Notes

This antibody binds to both JNK1 and JNK2 proteins of Mr=46 and 54 kDa.Full activation of JNK needs phosphorylation of a threonine and a tyrosine residue in the motif Thr-Pro-Tyr.

Scientific context

JNK is a main mitogen-activated protein kinases in mammals. Because of different mRNA splicing this protein is expressed as ten different isoforms. The most common isoforms are JNK1 and JNK2. JNK is activated by many signals in the cell such as growth factors, inflammatory cytokines, and environmental stress. The JNK pathway regulates the cell cycle, apoptotic and transcriptional responses to stress. Alternative names: Stress Activated Protein Kinase (SAPK)