c-Jun(Thr91+Thr93) Antibody, Cy3 Conjugated

bs-4601R-Cy3

0.1ml

368 EUR

Cy3

3725

IF(IHC-P)

anticorps

Polyclonal

1ug per 1ul

Thr91+Thr93

Phosphorylation

c-Jun Thr91+Thr93

Human, Mouse, Rat

Polyclonal antibody

cy3 conjugation kit

512,550nm/570,615nm

IF(IHC-P)(1:50-200)

Conjugated Primary Antibodies

Rabbit (Oryctolagus cuniculus)

This antibody was purified via Protein A.

c-Jun(Thr91+Thr93) Polyclonal Antibody, Cy3 Conjugated

This is a highly specific antibody against c-Jun Thr91+Thr93.

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

KLH conjugated synthetic phosphopeptide derived from human c-Jun around the phosphorylation site of (Thr91+Thr93)

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

p-c-JunThr91+Thr93; c-Jun phospho Thr91+Thr93; c-Jun phospho T91+T93; p-c-Jun Thr93; Jun oncogene; JUN; Activator Protein 1; AP 1; AP1; AP-1; Enhancer Binding Protein AP1; Jun Activation Domain Binding Protein; JUN protein; JUNC; p39; Proto oncogene cJun; Transcription Factor AP1; V jun avian sarcoma virus 17 oncogene homolog; vJun Avian Sarcoma Virus 17 Oncogene Homolog; JUN_HUMAN; Transcription factor AP-1; Activator 1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog.

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser. 1 of the Anti-c-Jun Thr91+Thr93 can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC. This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy.

C-jun (Oncoprotein C-jun) is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements and appears to be a major downstream target of the SAPK/JNK signaling pathway. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways. The MAP kinase homologue, SAPK/JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. In addition, the activity of SAPK/JNK is stimulated by the same signals that activate c-Jun.