anti-c-Jun antibody

Catalog no.

3009-100

Size

c-Jun antibody

Price

316 EUR

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Click here to buy anti-c-Jun antibody at gentaur.com

Target of this antibody:

c-Jun

This antibody reacts with:

Human

Antibody host:

Rabbit

Form of antibody:

Liquid

Shipping conditions:

gel pack

Concentration of antibody:

0.5 mg/ml

French translation

anticorps

Isotype:

Rabbit IgG

Clonality of antibody:

Polyclonal

This antibody has been succesfully tested for use in following methods:

Western blot

Purification method:

Affinity purified

Alternative names of antibody target:

JUN , AP1 , p39 , c-Jun

Storage information:

Shelf time: 12 months in temp.: -20 deg.C

How to handle this antibody:

The antibody solution should be gently mixed before use.

Immunogene sequence:

E. coli-expressed recombinant human c-Jun fusion protein

Properties

If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Formulation of this antibody:

100 µg (0.5 mg/ml) affinity purified rabbit anti-human c-Jun polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5mM EDTA and 0.01% thimerosal.

Recommended usage:

The antibody can be used in Western Blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Recombinant human c-Jun (Cat.# 7001-100) can be used as a positive control.

Background information:

c-Jun is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins, and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. The MAP kinase homologue, JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. The activity of JNK is stimulated by the same signals that activate c-Jun.